Byung-Hyun Park Selected Research

Insulinoma

9/2010	Sulfuretin protects against cytokine-induced beta-cell damage and prevents streptozotocin-induced diabetes.
7/2010	Nardostachys jatamansi extract protects against cytokine-induced beta-cell damage and streptozotocin-induced diabetes.
9/2009	Dihydroavenanthramide D protects pancreatic beta-cells from cytokine and streptozotocin toxicity.
2/2009	Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.
10/2008	Beneficial effect of Flos magnoliae extract on multiple low dose streptozotocin-induced type 1 diabetes development and cytokine-induced beta-cell damage.
9/2008	Radix clematidis extract protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathway.
7/2008	Guggulsterone, a plant sterol, inhibits NF-kappaB activation and protects pancreatic beta cells from cytokine toxicity.
11/2007	Genistein protects pancreatic beta cells against cytokine-mediated toxicity.
11/2007	Flavonoids protect against cytokine-induced pancreatic beta-cell damage through suppression of nuclear factor kappaB activation.
4/2007	Coptidis rhizoma extract protects against cytokine-induced death of pancreatic beta-cells through suppression of NF-kappaB activation.

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Byung-Hyun Park Research Topics

Disease

25	Inflammation (Inflammations) 06/2022 - 11/2008
25	Neoplasms (Cancer) 03/2022 - 03/2002
15	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 04/2015 - 05/2003
15	Insulinoma 09/2010 - 05/2003
14	Obesity 07/2020 - 12/2006
11	Necrosis 06/2022 - 08/2011
10	Insulin Resistance 01/2019 - 12/2013
9	Body Weight (Weight, Body) 04/2020 - 07/2006
9	Rheumatoid Arthritis 12/2018 - 04/2003
8	Carcinogenesis 01/2022 - 01/2009
7	Fibrosis (Cirrhosis) 06/2022 - 09/2004
7	Carcinoma (Carcinomatosis) 01/2020 - 12/2007
7	Arthritis (Polyarthritis) 12/2018 - 06/2008
6	Neoplasm Metastasis (Metastasis) 10/2021 - 02/2013
6	Breast Neoplasms (Breast Cancer) 01/2021 - 07/2009
6	Osteosarcoma (Osteogenic Sarcoma) 11/2020 - 09/2011
6	Hyperglycemia 01/2020 - 09/2007
6	Experimental Arthritis 03/2016 - 08/2010
5	Glucose Intolerance 04/2020 - 05/2014
5	Infections 11/2018 - 01/2002
5	Ischemia 01/2017 - 06/2008
4	Type 2 Diabetes Mellitus (MODY) 01/2020 - 07/2014
4	Hypoxia (Hypoxemia) 09/2017 - 04/2003
4	Experimental Melanoma 10/2012 - 06/2008
3	Liver Diseases (Liver Disease) 06/2022 - 01/2020
3	Reperfusion Injury 01/2022 - 06/2008
3	Psoriasis (Pustulosis Palmaris et Plantaris) 12/2021 - 01/2021
3	Bone Resorption 01/2021 - 03/2011
3	Osteoporosis 10/2020 - 01/2016
3	Hyperlipidemias (Hyperlipidemia) 06/2015 - 06/2008
3	Leukemia 07/2007 - 01/2002
2	Cholestasis 06/2022 - 04/2022
2	Stomach Neoplasms (Stomach Cancer) 05/2021 - 07/2009
2	Osteoarthritis 01/2021 - 04/2014
2	Dermatitis 01/2021 - 01/2021
2	Bone Diseases (Bone Disease) 10/2020 - 09/2017
2	Non-alcoholic Fatty Liver Disease 01/2018 - 01/2017
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 03/2017 - 03/2016
2	Hypertrophy 03/2017 - 12/2014

Drug/Important Bio-Agent (IBA)

26	CytokinesIBA 06/2022 - 05/2003
11	SirtuinsIBA 03/2022 - 07/2013
10	Proteins (Proteins, Gene)FDA Link 01/2022 - 12/2013
10	Insulin (Novolin)FDA Link 01/2021 - 09/2007
10	Sirtuin 1IBA 01/2018 - 10/2008
8	Glucose (Dextrose)FDA LinkGeneric 01/2021 - 10/2008
8	Streptozocin (Streptozotocin)FDA Link 04/2015 - 07/2006
8	Interleukin-1beta (Interleukin 1 beta)IBA 09/2010 - 05/2003
7	Interferon-gamma (Interferon, gamma)IBA 07/2010 - 05/2003
6	CateninsIBA 01/2022 - 01/2013
6	LipidsIBA 11/2016 - 09/2004
6	LeptinIBA 03/2015 - 09/2004
6	NF-kappa B (NF-kB)IBA 02/2011 - 04/2003
5	Indicators and Reagents (Reagents)IBA 10/2021 - 07/2009
5	Blood Glucose (Blood Sugar)IBA 07/2020 - 07/2015
5	AMP-Activated Protein KinasesIBA 01/2018 - 01/2015
4	EnzymesIBA 04/2020 - 06/2008
4	SPA0355IBA 01/2019 - 11/2013
4	Caspase 3 (Caspase-3)IBA 01/2019 - 01/2002
4	Transaminases (Aminotransferases)IBA 01/2017 - 08/2011
3	Therapeutic UsesIBA 06/2022 - 01/2014
3	Bile Acids and Salts (Bile Acids)IBA 06/2022 - 01/2020
3	NAD (NADH)IBA 03/2022 - 01/2022
3	Imiquimod (Aldara)FDA LinkGeneric 12/2021 - 01/2021
3	Pharmaceutical PreparationsIBA 12/2021 - 03/2002
3	Protein Kinases (Protein Kinase)IBA 01/2021 - 10/2015
3	Estrogens (Estrogen)FDA Link 10/2020 - 01/2019
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2019 - 06/2008
3	Phosphotransferases (Kinase)IBA 01/2018 - 05/2013
3	Metformin (Glucophage)FDA LinkGeneric 08/2016 - 12/2013
3	OvalbuminIBA 12/2014 - 09/2010
3	Matrix Metalloproteinases (MMPs)IBA 09/2013 - 05/2011
3	Complementary DNA (cDNA)IBA 07/2013 - 09/2004
3	pregna-4,17-diene-3,16-dione (guggulsterone)IBA 10/2012 - 06/2008
3	sulforaphaneIBA 09/2011 - 06/2008
3	Nitric Oxide (Nitrogen Monoxide)FDA Link 07/2008 - 01/2002
3	PerforinIBA 12/2007 - 01/2002
2	BilirubinIBA 06/2022 - 04/2022
2	Interleukin-23 (Interleukin 23)IBA 12/2021 - 01/2021
2	Histone Deacetylases (Histone Deacetylase)IBA 05/2021 - 01/2021
2	Cadherins (E-Cadherin)IBA 05/2021 - 01/2018
2	Small Interfering RNA (siRNA)IBA 01/2021 - 09/2013
2	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 01/2021 - 01/2021
2	Sirtuin 2IBA 01/2021 - 01/2017
2	olaparibIBA 11/2020 - 05/2018
2	Doxorubicin (Adriamycin)FDA LinkGeneric 11/2020 - 05/2018
2	AntioxidantsIBA 07/2020 - 09/2009
2	CholesterolIBA 01/2020 - 06/2015
2	CollagenIBA 01/2019 - 12/2018
2	Conditioned Culture MediaIBA 01/2019 - 01/2016
2	DNA (Deoxyribonucleic Acid)IBA 05/2018 - 01/2009
2	InterferonsIBA 01/2018 - 11/2007
2	Adenosine Monophosphate (AMP)IBA 01/2018 - 01/2018
2	VimentinIBA 01/2018 - 12/2007
2	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 01/2018 - 07/2015
2	buteinIBA 03/2017 - 01/2011
2	Insulin-Like Growth Factor I (IGF-1)IBA 03/2016 - 09/2008

Therapy/Procedure

6	Therapeutics 01/2021 - 02/2007
3	Ligation 06/2022 - 01/2020
2	Oral Administration 06/2022 - 04/2022
2	Intradermal Injections 12/2021 - 01/2021